Potent DNA-recombination method developed for large cargo delivery in gene therapy

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Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying gene cargoes because of their superior gene segmentation flexibility and robust gene reconstitution efficiency. However, their limited packaging capacity is a major challenge for large gene transduction.

Source: https://medicalxpress.com/news/2026-02- ... large.html
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