Small molecule blocks key glioblastoma driver, raising hopes for new treatment

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UVA Comprehensive Cancer Center scientists have identified a molecule that blocks the gene responsible for glioblastoma, raising hopes that the molecule could become a much-needed new treatment for the deadliest brain cancer. Researcher Hui Li, Ph.D., previously discovered the "oncogene" responsible for glioblastoma, a cancer for which there are no treatments that extend life for more than a few months. In his follow-up work, published in Science Translational Medicine, Li reports the identification of a small molecule that blocked the gene's activity in both cell samples and lab mice. In mice, the molecule proved effective without unwanted or harmful side effects.

Source: https://medicalxpress.com/news/2026-02- ... stoma.html
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