World's largest opioid review finds they often don't work

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The largest review ever conducted on opioids for acute pain found that these widely prescribed drugs often deliver only small, short-lived benefits. For many common conditions, including some surgeries and kidney stone pain, opioids performed no better than a placebo. Researchers also found higher rates of side effects and warned that dependence can begin after only a short period of use.

Source: https://www.sciencedaily.com/releases/2 ... 040023.htm
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